Saturday, November 15, 2008

29 - AIIMS november 2008 pediatrics mcqs - part 2

157.  a 7 yr old girl with non productive cough, mild stridor for 3 months duration. patient is improving but suddenly developed wheeze productive cough mild fever and hyperlucency on cxr and pft shows obstructive curve.diagnosis is? 
A. Bronchiolitis obliterans 
b. Hemosiderosis 
c. Pulmonary alveolar microlithiasis 
d. Follicular bronchitis 
 Answer: 

158. 3.5 kg term male baby born of uncomplicated pregnancy developed respiratory distress at birth not responded to surfactant, echo is normal, cxr shows ground glass appearance. Culture negative.apgar score 4 and 5 at 1 and 5 min.hostory of i month female sibling died before.diagnosis? 
A. Tapvc 
b. Meconium aspiration 
c. Neonatal plmonary alveolar proteinosis 
d. Diffuse herpes simplex infection 
 Answer: 

159. All are true about congenital rubella except? 
A. Igg persists for more than 6 months 
b. Igm antibody is present at birth 
c. Most common anomalies are hearing and heart defects 
d. Increased congenital malformation if infection after 16 weeks 
 Answer: 

160. A 10 yr old child is always restless inattentive to study and always wants to play outside.parents are extremely distressed.what would you advise? 
A. It’s a normalbehaviour 
b. Behaviour therapy 
c. It’s a serious illness requires medical treatment 
d. Needs change in environment 
Answer:

161.a 2yr old child brought to emergency at 3 am .child has barky cough and stridor only while crying. narmal hydration rr-36/min t-39.6 c .what will be your next step? 
a. racemic epinephrine nebulisation 
b. high dose dexamethasone inj 
c. nasal was for influenza/rsv 
d. antibiotics and blood culture 
 Answer: 

162.bad prognostic factor for all is? 
a. age 2-8 years 
b. TLC greater than 50000
c. hyperdiploidy 
d. t(9:22), t(8:14),t(4:11) 
 answer:

Wednesday, November 12, 2008

28 - AIIMS November 2008 Pediatrics mcqs - part 1

1Q: which of these statements is not correct ?
A. Neomycin is used as a preservative for BCG
B. kanamycin is use as a preservative for measles
C. magnesium chloride is used as a stabilizer for OPV
D. thimerosal is used as a preservative for DPT

answer: A .

let us analyse the options one by one

NEOMYCIN IS USED AS A PRESERVATIVE FOR BCG

The statement is FALSE

BCG contains glycerine, asparagine, citric acid, potassium phosphate, magnesium sulphate, and iron ammonium citrate. The final preparation prior to freeze-drying also contains lactose.

Sodium glutamate and chloride are also used as preservatives.

There is no neomycin

KANAMYCIN IS USE AS A PRESERVATIVE FOR MEASLES

The statement is TRUE

Yes , measles vaccine contains the antibiotics erythromycin and kanamycin.

Therefore , “kanamycin allergy is a definite contra indication to the measles vaccine ”

MAGNESIUM CHLORIDE IS USED AS A STABILISER IN OPV

That’s TRUE

Also remember

“Injectable polio vaccines do contain the antibiotics neomycin , streptomycin and polymyxin B but not oral polio vaccine !!! ”

Who knows …… this might be the question of 2009 !

THIMEROSAL IS USED AS A PRESERVATIVE IN DPT

YES that’s also true.

Thimerosal is a mercury derivative and hence raising a lot of controversies. It is used in certain other vaccines too.

WHAT IS SO CONTROVERSIAL ABOUT IT ?

Statistics indicate that AUTISM is on the rise. Researchers say that the use of thimerosal in several vaccines, especially DPT is directly related to the rise in autism !!!!

Composition of vaccines :

DPT: Aluminium phosphate, formaldehyde, ammonium sulphate, washed sheep red blood cells, glycerol, sodium chloride, thimerosal

Polio:
IPOL: 3 types of polio
virus, formaldehyde, henoxyethanol (antifreeze), neomycin, streptomycin, polymyxin B;
Orimune: using 3 types of attenuated polioviruses, streptomycin, neomycin, calf serum, sorbitol

HIB: polyribosylribitol, ammonium sulfate, thimerosal.

MMR: sorbitol, neomycin, hydrolyzed gelatin.

BCG: glycerine, asparagine, citric acid, potassium phosphate, magnesium sulphate, and iron ammonium citrate. The final preparation prior to freeze-drying also contains lactose.
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