1q: Which one of the listed clinical scenarios is most consistent with a
diagnosis of SIDS?
a. A 2-year-old female dies suddenly and no autopsy is performed
b. A 3-month-old female dies during sleep and the cause of death is unknown
after autopsy
c. A 4-week-old female dies from respiratory complications after being born 10
weeks prematurely
d. A 9-month-old male dies and an autopsy finds evidence of repeated bone fractures
and bilateral retinal hemorrhages
e. A male is stillborn at 29 weeks of gestation to a mother with obstetrical complications
*Sudden infant death syndrome :
(SIDS) is a heterogeneous, multifactorial disorder, but by definition it refers to sudden death of infant under 1 year of age that is unexplained after thorough examination. Most cases of SIDS occur between 2 and 4
months of life, and the child usually dies during sleep (“crib death” or “cot death”). A risk factor for SIDS is sleeping in a prone position. Therefore healthy infants should sleep on their back or side. Maternal factors associated with SIDS include age less than 20, being unmarried, low socioeconomic group, smoking, and drug abuse. Infant factors associated with SIDS include prematurity, low birth weight, male sex, and a history of SIDS in a sibling. In contrast to SIDS, death from respiratory complications after being born 10 weeks prematurely is suggestive of hyaline membrane disease, while evidence of repeated bone fractures and bilateral retinal hemorrhages is suggestive of trauma, child abuse, or “shaken baby” syndrome.
Showing posts with label pediatrics mcqs. Show all posts
Showing posts with label pediatrics mcqs. Show all posts
Thursday, October 2, 2008
Tuesday, March 25, 2008
20 - Paediatrics Mcqs - 152 to 165
152 - Which of the following does not establish a diagnosis of congenital CMV infection in a neonate?
A. Urine culture of CMV
B. IgG CMV antibodies in blood
C. Intra-nuclear inclusion bodies in hepatocytes
D. CMV viral DNA in blood by polymerase chain reaction
(Ref: Cloherty’s Manual of Neonatal Care 5th Ed/P-257)
153 - All of the following are true of β thalassemia major, except:
A. Splenomegaly
B. Target cells on peripheral smear
C. Microcytic hypochromic anemia
D. Increased osmotic fragility
(Ref: Manual of Pediatric Hematology and Oncology, 4th Ed/P-184)
154 - Transient synovitis (toxic synovitis) of the hip is characterized by all of the following, except:
A. May follow upper respiratory infection
B. ESR and white blood cell counts are usually normal
C. Ultrasound of the joint reveals widening of the joint space
D. The hip is typically held in adduction and internal rotation
(Ref: Nelson’s Textbook of Pediatrics 17th Ed, Ch. 148, P-809)
155 - A 3-year-old boy presents with fever, dysuria and gross hematuria. Physical examination shows a prominent suprapubic area which is dull to percussion. Urinalysis reveals red blood cells but no proteinuria. Which of the following is the most likely diagnosis?
A. Acute glomerulonephritis
B. Urinary tract infection
C. Posterior urethral valves
D. Teratoma
156 - Which of the following statements is true of primary grade IV-V vesicoureteric reflux in young children?
A. Renal scarring usually begins in the midpolar regions
B. Postnatal scarring may occur even in the absence of urinary tract infections
C. Long-term outcome is comparable in patients treated with either antibiotic prophylaxis or surgery
D. Oral amoxicillin is the choice antibiotic for prophylaxis
(Ref: Nelson’s Textbook of Pediatrics 17th Ed—Ch. 531-Vesicoureteric Reflux, P-1791-1793)
157 - 15-year-old boy presented with one day history of bleeding gums, subconjunctival bleed and purpuric rash. Investigations revealed the following results:
Hb-6.4 gm/dL; TLC-26,500/mm3 Platelet-35,000/mm3; prothrombin time–20 sec with a control of 13 sec; partial thromboplastin time-50 sec; and Fibrinogen 10 mg/dL. Peripheral smear was suggestive of acute myeloblastic leukemia. Which of the following is the most likely?
A. Myeloblastic leukemia without maturation
B. Myeloblastic leukemia with maturation
C. Promyelocytic leukemia
D. Myelomonscytic leukemia
*The type of AML, which is most commonly associated with DIC is AML M3.
(Ref: Manual of Pediatric Hematology and Oncology, 4th Ed/P-306, 443)
158 - The defective migration of neural crest cells results in:
A. Congenital megacolon
B. Albinism
C. Adrenogenital hypoplasia
D. Dentinogenesis imperfecta
(Ref: Schwartz’s Principles of Surgery 8th Ed. 2005— Part II- Specific Considerations; Ch. 38-Pediatric Surgery)
159 - A premature infant is born with a patent ductus arteriosus. Its closure can be stimulated by administration of:
A. Prostaglandin analogue
B. Estrogen
C. Anti-estrogen compounds
D. Prostaglandin inhibitors
160 - The loading dose of Aminophylline is:
A. 50-75 ug/kg
B. 0.5-1.0 mg/kg
C. 2.0-3.5 mg/kg
D. 5-6 mg/kg
161 - Cushing’s Triad includes all except:
A. Hypertension
B. Bradycardia
C. Hypothermia
D. Irregular respiration
(Ref: Current Pediatric Diagnosis and Treatment 17th Ed. 2005—Ch. 11-Emergencies and Injuries)
162 - All of the following drugs are used for managing status epilepticus except:
A. Phenytoin
B. Diazepam
C. Thiopentone sodium
D. Carbamazepine
(Ref: Current Pediatric Diagnosis and Treatment 17th Ed. 2005—Ch. 23-Neurologic and Muscular Disorders; Table 23.9-Status epilepticus treatment)
163 - Administration of glucose solution is prescribed for all of the following situations except:
A. Neonates
B. Child of a diabetic mother
C. History of unconsciousness
D. History of hypoglycemia
(Ref: Rudolph’s Pediatrics 21st Ed. 2003—24. The Endocrine System; 24.9-Hypoglycemia)
164 - Which organ is the primary site of hematopoiesis in the fetus before midpregnancy?
A. Bone
B. Liver
C. Spleen
D. Lung
(Ref: Nelson’s Textbook of Pediatrics 17th Ed/
P-1599)
165 - All of the following are the complications in the new born of a diabetic mother except:
A. Hyperbilirubinemia
B. Hyperglycemia
C. Hypocalcemia
D. Hypomagnesemia
(Ref: Cloherty’s Manual of Neonatal Care 5th Ed./P-13-1.
McQs in Paediatrics (Pocket MCQs)
Paediatric McQs for Postgraduate Examinations: Practice Examinations
McQs in Paediatrics: With a Tactical Guide on How to Approach Clinical Examinations (PMCQ)
A. Urine culture of CMV
B. IgG CMV antibodies in blood
C. Intra-nuclear inclusion bodies in hepatocytes
D. CMV viral DNA in blood by polymerase chain reaction
(Ref: Cloherty’s Manual of Neonatal Care 5th Ed/P-257)
153 - All of the following are true of β thalassemia major, except:
A. Splenomegaly
B. Target cells on peripheral smear
C. Microcytic hypochromic anemia
D. Increased osmotic fragility
(Ref: Manual of Pediatric Hematology and Oncology, 4th Ed/P-184)
154 - Transient synovitis (toxic synovitis) of the hip is characterized by all of the following, except:
A. May follow upper respiratory infection
B. ESR and white blood cell counts are usually normal
C. Ultrasound of the joint reveals widening of the joint space
D. The hip is typically held in adduction and internal rotation
(Ref: Nelson’s Textbook of Pediatrics 17th Ed, Ch. 148, P-809)
155 - A 3-year-old boy presents with fever, dysuria and gross hematuria. Physical examination shows a prominent suprapubic area which is dull to percussion. Urinalysis reveals red blood cells but no proteinuria. Which of the following is the most likely diagnosis?
A. Acute glomerulonephritis
B. Urinary tract infection
C. Posterior urethral valves
D. Teratoma
156 - Which of the following statements is true of primary grade IV-V vesicoureteric reflux in young children?
A. Renal scarring usually begins in the midpolar regions
B. Postnatal scarring may occur even in the absence of urinary tract infections
C. Long-term outcome is comparable in patients treated with either antibiotic prophylaxis or surgery
D. Oral amoxicillin is the choice antibiotic for prophylaxis
(Ref: Nelson’s Textbook of Pediatrics 17th Ed—Ch. 531-Vesicoureteric Reflux, P-1791-1793)
157 - 15-year-old boy presented with one day history of bleeding gums, subconjunctival bleed and purpuric rash. Investigations revealed the following results:
Hb-6.4 gm/dL; TLC-26,500/mm3 Platelet-35,000/mm3; prothrombin time–20 sec with a control of 13 sec; partial thromboplastin time-50 sec; and Fibrinogen 10 mg/dL. Peripheral smear was suggestive of acute myeloblastic leukemia. Which of the following is the most likely?
A. Myeloblastic leukemia without maturation
B. Myeloblastic leukemia with maturation
C. Promyelocytic leukemia
D. Myelomonscytic leukemia
*The type of AML, which is most commonly associated with DIC is AML M3.
(Ref: Manual of Pediatric Hematology and Oncology, 4th Ed/P-306, 443)
158 - The defective migration of neural crest cells results in:
A. Congenital megacolon
B. Albinism
C. Adrenogenital hypoplasia
D. Dentinogenesis imperfecta
(Ref: Schwartz’s Principles of Surgery 8th Ed. 2005— Part II- Specific Considerations; Ch. 38-Pediatric Surgery)
159 - A premature infant is born with a patent ductus arteriosus. Its closure can be stimulated by administration of:
A. Prostaglandin analogue
B. Estrogen
C. Anti-estrogen compounds
D. Prostaglandin inhibitors
160 - The loading dose of Aminophylline is:
A. 50-75 ug/kg
B. 0.5-1.0 mg/kg
C. 2.0-3.5 mg/kg
D. 5-6 mg/kg
161 - Cushing’s Triad includes all except:
A. Hypertension
B. Bradycardia
C. Hypothermia
D. Irregular respiration
(Ref: Current Pediatric Diagnosis and Treatment 17th Ed. 2005—Ch. 11-Emergencies and Injuries)
162 - All of the following drugs are used for managing status epilepticus except:
A. Phenytoin
B. Diazepam
C. Thiopentone sodium
D. Carbamazepine
(Ref: Current Pediatric Diagnosis and Treatment 17th Ed. 2005—Ch. 23-Neurologic and Muscular Disorders; Table 23.9-Status epilepticus treatment)
163 - Administration of glucose solution is prescribed for all of the following situations except:
A. Neonates
B. Child of a diabetic mother
C. History of unconsciousness
D. History of hypoglycemia
(Ref: Rudolph’s Pediatrics 21st Ed. 2003—24. The Endocrine System; 24.9-Hypoglycemia)
164 - Which organ is the primary site of hematopoiesis in the fetus before midpregnancy?
A. Bone
B. Liver
C. Spleen
D. Lung
(Ref: Nelson’s Textbook of Pediatrics 17th Ed/
P-1599)
165 - All of the following are the complications in the new born of a diabetic mother except:
A. Hyperbilirubinemia
B. Hyperglycemia
C. Hypocalcemia
D. Hypomagnesemia
(Ref: Cloherty’s Manual of Neonatal Care 5th Ed./P-13-1.
McQs in Paediatrics (Pocket MCQs)
Paediatric McQs for Postgraduate Examinations: Practice Examinations
McQs in Paediatrics: With a Tactical Guide on How to Approach Clinical Examinations (PMCQ)
19 - Paediatrics Mcqs - 141 to 151
141 - Conjugated hyperbilirubinemia is seen in:
A. Gilbert’s syndrome
B. Griggler Najjar syndrome
C. Breast milk jaundice
D. Dubin Johnson syndrome
Ans. (D) Dubin Johnson syndrome
(Ref: Nelson’s Textbook of Pediatrics 17th Ed, Ch. 338, P-1321)
142 - A 15-year-old female presented to the emergency department with history of recurrent epistaxis, hematuria and hematochezia. There was a history of profuse bleeding from the umbilicus stump at birth. Previous investigations revealed normal prothrombin time, activated partial thromboplastin time, thrombin time and fibrinogen levels. Her platelet counts as well as platelet function tests were normal but urea c1ot Jt. positive. Which one of the following clotting factor is most likely to be deficient?
A. Factor X
B. Factor XI
C. Factor XII
D. Factor XIII
Ans. (D) Factor XIII
(Ref: Nelson Pediatrics 17th Ed/P-1661)
143 - Which one of the following is the characteristic feature of juvenile myoclonic epilepsy?
A. Myoclonic seizures frequently occur in morning
B. Complete remission is common
C. Response to anticonvulsants is poor
D. Associated absence seizures are present in majority of patients
Ans. (A) Myoclonic seizures frequently occur in the morning
(Ref: Harrison’s Principles of Internal Medicine 16th Ed. 2005—Part XV-Neurologic Disorders;Sec. 2-Diseases of the Central Nervous System;Ch. 348-Seizures and Epilepsy)
*Here is a short notes on Juvenile Myoclonic Epilepsy (Janz syndrome)
144 - Plethoric lung fields are seen in all of the following conditions, except:
A. Atrial septal defect (ASD)
B. TAPVC (Total Anomalous Pulmonary venous connection)
C. Ebstein’s anomaly
D. Ventricular septal defect
Ans. (C) Ebstein’s anomaly
(Ref: Review of Radiology 3rd Ed/p-42-43)
145 - Which of the following is an example of disorders of sex chromosomes?
A. Marfan’s syndrome
B. Testicular feminization syndrome
C. Klinefelter’ s syndrome
D. Down’s syndrome
Ans. (C) Klinefelter’ s syndrome
(Ref: Robbins and Cotrans’s Pathologic Basis of Disease 7th Ed/P-145)
146 - Which of the following haemoglobin (Hb) estimation will be diagnostically helpful in a case of beta thalassemia trait?
A. Hb-F
B. Hb1C
C. Hb-A2
D. Hb-H
Ans. (C) Hb-A2
(Ref: Nelsons Pediatrics 17th Ed/P-1633)
147 - Which of the following circulating antibodies has the best sensitivity and specificity for the diagnosis of celiac disease?
A. Anti-endomysial antibody
B. Anti-tissue transglutaminase antibody
C. Anti-gliadin antibody
D. Anti-reticulin antibody
Ans. (A) Anti-endomysial antibody
(Ref: Nelsons Pediatrics 17th Ed/P-1265)
148 - A couple has two children affected with tuberous sclerosis. On detailed clinical and laboratory evaluation (including molecular studies) both parents are normal. Which one of the following explains the two affected children in this family?
A. Non penetrance
B. Uniparental diasomy
C. Genomic imprinting
D. Germline mosaicism
Ans. (D) Germline Mosaicism
(Ref: Journal of Child Neurology/Vol. 19, No. 9, Sept. 2004)
149 - Cardiomyopathy may be seen in all of the following except:
A. Duchenne muscular dystrophy
B. Friedreich’s ataxia
C. Type II glycogen storage disease
D. Alkaptonuria
Ans. (D) Alkaptonuria
150 - Enzyme replacement therapy is available for which of the following disorders?
A. Gaucher disease
B. Niemann Pick disease
C. Mucolipidosis
D. Metachromatic leukodystrophy
Ans. (A) Gaucher’s disease.
151 - In a child with acute liver failure, the most important prognostic factor for death is:
A. Increasing transaminases
B. Increasing bilirubin
C. Increasing prothrombin time
D. Gram negative sepsis
Ans. (C) Prothrombin time.
(Ref: Diseases of the liver and the biliary system 11th Ed, Ch. 8-Acute Liver Failure, P-118)
A. Gilbert’s syndrome
B. Griggler Najjar syndrome
C. Breast milk jaundice
D. Dubin Johnson syndrome
Ans. (D) Dubin Johnson syndrome
(Ref: Nelson’s Textbook of Pediatrics 17th Ed, Ch. 338, P-1321)
142 - A 15-year-old female presented to the emergency department with history of recurrent epistaxis, hematuria and hematochezia. There was a history of profuse bleeding from the umbilicus stump at birth. Previous investigations revealed normal prothrombin time, activated partial thromboplastin time, thrombin time and fibrinogen levels. Her platelet counts as well as platelet function tests were normal but urea c1ot Jt. positive. Which one of the following clotting factor is most likely to be deficient?
A. Factor X
B. Factor XI
C. Factor XII
D. Factor XIII
Ans. (D) Factor XIII
(Ref: Nelson Pediatrics 17th Ed/P-1661)
143 - Which one of the following is the characteristic feature of juvenile myoclonic epilepsy?
A. Myoclonic seizures frequently occur in morning
B. Complete remission is common
C. Response to anticonvulsants is poor
D. Associated absence seizures are present in majority of patients
Ans. (A) Myoclonic seizures frequently occur in the morning
(Ref: Harrison’s Principles of Internal Medicine 16th Ed. 2005—Part XV-Neurologic Disorders;Sec. 2-Diseases of the Central Nervous System;Ch. 348-Seizures and Epilepsy)
*Here is a short notes on Juvenile Myoclonic Epilepsy (Janz syndrome)
144 - Plethoric lung fields are seen in all of the following conditions, except:
A. Atrial septal defect (ASD)
B. TAPVC (Total Anomalous Pulmonary venous connection)
C. Ebstein’s anomaly
D. Ventricular septal defect
Ans. (C) Ebstein’s anomaly
(Ref: Review of Radiology 3rd Ed/p-42-43)
145 - Which of the following is an example of disorders of sex chromosomes?
A. Marfan’s syndrome
B. Testicular feminization syndrome
C. Klinefelter’ s syndrome
D. Down’s syndrome
Ans. (C) Klinefelter’ s syndrome
(Ref: Robbins and Cotrans’s Pathologic Basis of Disease 7th Ed/P-145)
146 - Which of the following haemoglobin (Hb) estimation will be diagnostically helpful in a case of beta thalassemia trait?
A. Hb-F
B. Hb1C
C. Hb-A2
D. Hb-H
Ans. (C) Hb-A2
(Ref: Nelsons Pediatrics 17th Ed/P-1633)
147 - Which of the following circulating antibodies has the best sensitivity and specificity for the diagnosis of celiac disease?
A. Anti-endomysial antibody
B. Anti-tissue transglutaminase antibody
C. Anti-gliadin antibody
D. Anti-reticulin antibody
Ans. (A) Anti-endomysial antibody
(Ref: Nelsons Pediatrics 17th Ed/P-1265)
148 - A couple has two children affected with tuberous sclerosis. On detailed clinical and laboratory evaluation (including molecular studies) both parents are normal. Which one of the following explains the two affected children in this family?
A. Non penetrance
B. Uniparental diasomy
C. Genomic imprinting
D. Germline mosaicism
Ans. (D) Germline Mosaicism
(Ref: Journal of Child Neurology/Vol. 19, No. 9, Sept. 2004)
149 - Cardiomyopathy may be seen in all of the following except:
A. Duchenne muscular dystrophy
B. Friedreich’s ataxia
C. Type II glycogen storage disease
D. Alkaptonuria
Ans. (D) Alkaptonuria
150 - Enzyme replacement therapy is available for which of the following disorders?
A. Gaucher disease
B. Niemann Pick disease
C. Mucolipidosis
D. Metachromatic leukodystrophy
Ans. (A) Gaucher’s disease.
151 - In a child with acute liver failure, the most important prognostic factor for death is:
A. Increasing transaminases
B. Increasing bilirubin
C. Increasing prothrombin time
D. Gram negative sepsis
Ans. (C) Prothrombin time.
(Ref: Diseases of the liver and the biliary system 11th Ed, Ch. 8-Acute Liver Failure, P-118)
18 - Pediatric Pulmonology mcqs - Question 1
1. A 10 year old boy has a 1 year history of cough that is worse at night and with exercise.Which one of the following tests is most likely to assist you to make a diagnosis:
A-Barium swallow.
B-Bronchoscopy.
C-Chest radiograph.
D-Spirometry.
E-Sweat chloride test.
the answer is d . as the diagnosis is in favour of bronchial asthma the answer is d.
Essential Pediatric McQs
MCQs in Pediatrics 2nd edition
MCQs in Pediatrics ; Over 600 Questions with Explanatory Notes
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